Encorafenib + Cetuximab Beyond Progression in Combination With FOLFIRI in Patients With BRAF V600E Mutated Metastatic Colorectal Cancer Progressing on Encorafenib + Cetuximab.

The aim of this study is to determine the activity of encorafenib plus cetuximab in combination with FOLFIRI in patients with BRAF V600E mutated metastatic colorectal cancer progressing on encorafenib plus cetuximab administered in second line.

Trial Details

NCT ID
NCT06640166
Phase
PHASE2
Sponsor
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Status
RECRUITING
Cancer Type
Colorectal Cancer
Interventions
  • encorafenib + cetuximab + FOLFIRI
Locations (sample)
  • Milan, Italy|42.78235,12.59836
  • Roma, Italy|44.99364,11.10642
  • Tricase, Italy|39.93018,18.35421

Key Eligibility Criteria

  • written informed consent to study procedures;
  • age ≥ 18 years;
  • histologically or cytologically confirmed diagnosis of colorectal adenocarcinoma;
  • radiological evidence of metastatic disease;

For full eligibility, visit ClinicalTrials.gov.

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