Hypofractionated Radiotherapy Before or After Breast Surgery for Treatment of Patients With Non-Metastatic Breast Cancer

This phase II trial studies how well hypofractionated radiotherapy before (preoperative) or after (postoperative) breast surgery works in treating patients with different types of non-metastatic (has not spread from original tumor site) breast cancer and to determine the outcomes and side effects of this treatment. Radiation therapy is considered an integral part of breast conserving therapy. Hypofractionated radiation therapy is a radiation treatment in which the total dose of radiation is divided into large doses and treatments are given less than once a day. This has been shown to be an eff

Trial Details

NCT ID
NCT06635980
Phase
PHASE2
Sponsor
Mayo Clinic
Status
RECRUITING
Cancer Type
Triple Negative (TNBC) Breast Cancer
Interventions
  • Biopsy of Breast
  • Biospecimen Collection
  • Breast Surgery
  • Chemotherapy
  • Computed Tomography
  • Contrast Enhanced Digital Mammography
Locations (sample)
  • Scottsdale, Arizona, United States|33.50921,-111.89903

Key Eligibility Criteria

  • Age \>= 18 years
  • Histological confirmation of breast cancer
  • Clinical stage T1-T4 N0-3 M0
  • Eastern Cooperative Oncology Group (ECOG) performance status (PS) 0 to 2

For full eligibility, visit ClinicalTrials.gov.

Check If You May Be Eligible

Trialify translates complex eligibility criteria into plain yes-or-no questions to help you understand if this trial might be right for you.

Find Triple Negative (TNBC) Breast Cancer Trials on Trialify →