Antibiotic Treatment Effects on Intratumoral Bacteria Modulation in Surgical Patients With Oral Cancer

The goal of this phase II single arm clinical study is to evaluate the effect of antibiotics (metronidazole) and oral chlorhexidine (CHX) in reducing the bacteria load within tumors of patients undergoing surgery for oral cancer.

Trial Details

NCT ID

NCT06627270

Phase

PHASE2

Sponsor

Case Comprehensive Cancer Center

Status

RECRUITING

Cancer Type

Head and Neck Cancer

Interventions

Metronidazole
Chlorhexidine

Locations (sample)

Cleveland, Ohio, United States|41.4995,-81.69541

Key Eligibility Criteria

Pathologically confirmed squamous cell carcinoma of the oral cavity
Must have planned surgery for curative intent
Participants ≥ 18 years of age
Participants must have the ability to understand and the willingness to sign a written informed consent document

For full eligibility, visit ClinicalTrials.gov.

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