Radiation Therapy With RapidPlan Knowledge-based Planning vs Human-Driven Planning for Treatment of Prostate Cancer

This phase III trial compares the effects of radiation therapy using RapidPlan, trademark, knowledge-based planning to human-driven planning in treating patients with prostate cancer. Radiation therapy uses high energy x-rays, particles, or radioactive seeds to kill tumor cells and shrink tumors. Successful delivery of radiation requires planning to develop a treatment plan for how and where the radiation is to be delivered. RapidPlan is a knowledge-based treatment planning tool that automatically creates an optimal treatment plan based on identified targets and organs at risk for radiation ex

Trial Details

NCT ID
NCT06625034
Phase
PHASE3
Sponsor
Mayo Clinic
Status
RECRUITING
Cancer Type
Prostate Cancer
Interventions
  • Biospecimen Collection
  • Magnetic Resonance Imaging
  • Photon Beam Radiation Therapy
  • Positron Emission Tomography
  • Questionnaire Administration
  • Radiation Therapy Treatment Planning and Simulation
Locations (sample)
  • Scottsdale, Arizona, United States|33.50921,-111.89903
  • Jacksonville, Florida, United States|30.33218,-81.65565

Key Eligibility Criteria

  • Patients must be at least 18 years old
  • Histologically confirmed prostate cancer
  • Clinical or pathologic stages T1c-T3b, Nx or N0-1, M0-1 (American Joint Committee on Cancer \[AJCC\] criteria 8th edition \[Ed\])
  • Planned definitive dose radiotherapy to the prostate or prostate bed

For full eligibility, visit ClinicalTrials.gov.

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