A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)

The purpose of this study is to compare the efficacy and safety of arlo-cel (BMS-986393) versus standard regimens in adult participants with Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma.

Trial Details

NCT ID
NCT06615479
Phase
PHASE3
Sponsor
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
Status
RECRUITING
Cancer Type
Relapsed/Refractory Multiple Myeloma
Interventions
  • BMS-986393
  • Cyclophosphamide
  • Fludarabine
  • Daratumumab
  • Pomalidomide
  • Dexamethasone
Locations (sample)
  • Birmingham, Alabama, United States|33.52066,-86.80249
  • Los Angeles, California, United States|34.05223,-118.24368
  • Orange, California, United States|33.78779,-117.85311
  • Washington D.C., District of Columbia, United States|38.89511,-77.03637
  • Jacksonville, Florida, United States|30.33218,-81.65565

Key Eligibility Criteria

  • Participants must have relapsed or refractory multiple myeloma (RRMM).
  • Participants must have received at least 1 but no greater than 3 prior multiple myeloma (MM) regimens which may include a proteasome inhibitor (PI)…
  • Participants must have a documented diagnosis of MM as per International Myeloma Working Group Criteria.
  • Participants must have measurable disease during screening.

For full eligibility, visit ClinicalTrials.gov.

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