Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed).

Study in children and adolescents of 177Lu DOTATATE (Lutathera®) combined with the PARP inhibitor olaparib for treatment of recurrent or relapsed solid tumours expressing somatostatin receptors (SSTR) (LuPARPed)

Trial Details

NCT ID
NCT06607692
Phase
PHASE1 / PHASE2
Sponsor
Fundación de investigación HM
Status
RECRUITING
Cancer Type
Osteosarcoma Sarcoma
Interventions
  • Olaparib; 177Lu-DOTATATE
Locations (sample)
  • Boadilla del Monte, Madrid, Spain|40.405,-3.87835

Key Eligibility Criteria

  • 18 months - 18 years of age at the time of the initial diagnosis.
  • ≥ 3 years at the moment of inclusion in the trial.
  • Diagnosis: relapsed/refractory solid tumours with positive uptake on SSTR-PET (PET-CT or PET-MRI), performed in the previous three months before en…
  • The evaluation of SSTR expression will be classified according to a qualitative 4-point scale: SSTR expression V (visual score):

For full eligibility, visit ClinicalTrials.gov.

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