Postoperative Radiotherapy for Intermediate- and High-risk Patients With HNSCC Greater Than 6 Weeks After Surgery

The goal of this clinical trial is to determine whether accelerated radiotherapy (involving 6 treatments per week) is better than standard radiotherapy (involving 5 treatments per week) at treating cancer of the head and neck when initiated more than 6 weeks after surgery.

Trial Details

NCT ID
NCT06607406
Phase
NA
Sponsor
Wake Forest University Health Sciences
Status
RECRUITING
Cancer Type
Head and Neck Cancer
Interventions
  • Accelerated radiotherapy
  • Conventional radiotherapy
Locations (sample)
  • Charlotte, North Carolina, United States|35.22709,-80.84313
  • Winston-Salem, North Carolina, United States|36.09986,-80.24422
  • Milwaukee, Wisconsin, United States|43.0389,-87.90647

Key Eligibility Criteria

  • Pathologically confirmed head and neck squamous cell carcinoma of the oral cavity, oropharynx, larynx, hypopharynx, sinus, or lymph nodes of the ne…
  • Planned for curative intent postoperative radiotherapy based on pathologic risk factors.
  • Patients with non-HPV-mediated oropharyngeal squamous cell carcinoma or non-oropharyngeal squamous cell carcinoma must have at least one of the fol…
  • Patients with HPV-mediated oropharyngeal squamous cell carcinoma must have at least one of the following pathologic risk factors: extranodal extens…

For full eligibility, visit ClinicalTrials.gov.

Check If You May Be Eligible

Trialify translates complex eligibility criteria into plain yes-or-no questions to help you understand if this trial might be right for you.

Find Head and Neck Cancer Trials on Trialify →