Cryodevitalization for the Treatment of Early Stage Lung Cancer, CRYSTAL Trial

This clinical trial studies side effects and best treatment time of cryodevitalization in treating patients with early stage (stage I or stage II) lung cancer. Cryodevitalization is a type of cryosurgery that uses a flexible probe (cryoprobe) to kill tumor cells by freezing them. It is delivered at the time of standard diagnostic robotic bronchoscopy. Using cryodevitalization may be safe, tolerable and/or effective in treating patients with early stage lung cancer.

Trial Details

NCT ID
NCT06593106
Phase
NA
Sponsor
Vanderbilt-Ingram Cancer Center
Status
RECRUITING
Cancer Type
Lung Cancer
Interventions
  • Cryosurgery
  • Robotic Bronchoscopy
  • Bronchoscopy with Biopsy
  • Resection
  • Chest Radiography
  • Computed Tomography
Locations (sample)
  • Nashville, Tennessee, United States|36.16589,-86.78444

Key Eligibility Criteria

  • Patients with a single pulmonary nodule with a size less than or equal to three centimeters (average long and short axis) confirmed as malignant in…
  • Nodules must be located in the outer 2/3 of the periphery of the lung, greater than 10 mm from the pleura and from large blood vessels or mediastin…
  • Patients deemed to have a surgical resection treatment option based on preoperative staging computed tomographic (CT), postoperative predicted forc…
  • Age \> 18 years old

For full eligibility, visit ClinicalTrials.gov.

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