Vebreltinib Plus PLB1004 as the First-line Therapy for Patients With EGFRm+/MET+ Locally Advanced or Metastatic NSCLC.

Efficacy and Safety Evaluation of Vebreltinib Plus PLB1004 as the First-line Therapy for Patients With EGFRm+/MET+ Locally Advanced or Metastatic NSCLC.

Trial Details

NCT ID
NCT06574347
Phase
PHASE2
Sponsor
Avistone Biotechnology Co., Ltd.
Status
RECRUITING
Cancer Type
Lung Cancer
Interventions
  • Vebreltinib
  • Osimertinib
  • PLB1004
Locations (sample)
  • Guangzhou, Guangdong, China|23.11667,113.25

Key Eligibility Criteria

  • Ability to understand and willingness to sign a written informed consent document.
  • Aged at least 18 years old.
  • Histologically or cytologically confirmed locally advanced or metastatic NSCLC (stage IIIB\~IV).
  • Patients with previously untreated, EGFRm-positive (exon 19 deletion or L858R) and MET overexpression (IHC 3+) .

For full eligibility, visit ClinicalTrials.gov.

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