Study of Volrustomig as Monotherapy or in Combination With Anti- Cancer Agents in Participants With Advanced/Metastatic Solid Tumors

eVOLVE-02 study will evaluate the efficacy and safety of volrustomig as monotherapy or in combination with anti-cancer agents in participants with advanced/metastatic solid tumors.

Trial Details

NCT ID
NCT06535607
Phase
PHASE2
Sponsor
AstraZeneca
Status
RECRUITING
Cancer Type
Head and Neck Cancer
Interventions
  • Volrustomig
  • Cisplatin
  • Carboplatin
  • Paclitaxel
  • 5-FU
Locations (sample)
  • Los Angeles, California, United States|34.05223,-118.24368
  • Baltimore, Maryland, United States|39.29038,-76.61219
  • New York, New York, United States|40.71427,-74.00597
  • Stony Brook, New York, United States|40.92565,-73.14094
  • Columbus, Ohio, United States|39.96118,-82.99879

Key Eligibility Criteria

  • Age ≥18 at the time of signing the ICF.
  • Provision of tumor sample to assess the PD-L1 expression (if applicable).
  • ECOG performance status of 0 or 1.
  • Measurable disease according to RECIST 1.1 (variations of RECIST 1.1 if applicable).

For full eligibility, visit ClinicalTrials.gov.

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