Salvage MR-guided High-Dose-Rate Brachytherapy for Prostate Bed Recurrence After Radiotherapy in the PSMA PET Scan Era

This is an interventional, single-centre, single-arm, non-randomized, prospective, feasibility trial investigating salvage MR-guided High-Dose-Rate brachytherapy for prostate bed recurrence after postoperative radiotherapy.

Trial Details

NCT ID
NCT06508567
Phase
NA
Sponsor
University Health Network, Toronto
Status
RECRUITING
Cancer Type
Prostate Cancer
Interventions
  • High Dose Rate Brachytherapy
Locations (sample)
  • Toronto, Ontario, Canada|43.65333,-79.38389

Key Eligibility Criteria

  • Patients who received previous RT to the prostate bed +/- pelvic nodal regions
  • Prostate-bed recurrence identified by biopsy and/or MRI and/or PSMA-PET scan
  • At least two continuous PSA elevations post RT and PSA above 0.2 ng/dl
  • With or without ADT PSA doubling time from nadir greater than 6 months

For full eligibility, visit ClinicalTrials.gov.

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