Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain

This phase III trial compares the effectiveness of fractionated stereotactic radiosurgery (FSRS) to usual care stereotactic radiosurgery (SRS) in treating patients with cancer that has spread from where it first started to the brain. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors. FSRS delivers a high dose of radiation to the tumor over 3 treatments. SRS is a type of external radiation therapy that uses special equipment to position the patient and precisely give a single large dose of radiation to a tumor. FSRS may be more effective compared to SRS in treating

Trial Details

NCT ID
NCT06500455
Phase
PHASE3
Sponsor
NRG Oncology
Status
RECRUITING
Cancer Type
Adenocarcinoma Lung Cancer
Interventions
  • Computed Tomography
  • Fractionated Stereotactic Radiation Therapy
  • Magnetic Resonance Imaging
  • Stereotactic Radiosurgery
Locations (sample)
  • Tucson, Arizona, United States|32.22174,-110.92648
  • Fort Smith, Arkansas, United States|35.38592,-94.39855
  • Anaheim, California, United States|33.83529,-117.9145
  • Los Angeles, California, United States|34.05223,-118.24368
  • Aurora, Colorado, United States|39.72943,-104.83192

Key Eligibility Criteria

  • Pathologically (histologically or cytologically) proven diagnosis of one of the following solid tumor malignancies within 5 years prior to registra…
  • Non-small cell lung cancer
  • Breast cancer
  • Renal cell carcinoma

For full eligibility, visit ClinicalTrials.gov.

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