Ivonescimab(AK112/SMT112) in Combination With Stereotactic Body Radiation Therapy and Chemotherapy in Patients With Pancreatic Cancer

This study is an open-label, single-arm Phase II clinical study to evaluate the efficacy and safety of ivonescimab(AK112/SMT112) in combination with stereotactic body radiation therapy and chemotherapy in patients with pancreatic cancer

Trial Details

NCT ID
NCT06491472
Phase
PHASE2
Sponsor
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Status
RECRUITING
Cancer Type
Pancreatic Cancer
Interventions
  • Ivonescimab
  • Gemcitabine
  • Nab paclitaxel
  • SBRT
Locations (sample)
  • Wuhan, China|30.58333,114.26667

Key Eligibility Criteria

  • Be able and willing to provide written informed consent and comply with all requirements of study participation (including all study procedures).
  • Histologically- or cytologically-confirmed diagnosis of pancreatic ductal adenocarcinoma (including adenosquamous carcinoma)
  • Have a life expectancy of at least 3 months.
  • Have an Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1

For full eligibility, visit ClinicalTrials.gov.

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