German-funded Laparoscopic Approach to Cervical Cancer

The G-LACC trial is a prospective, interventional, multicenter, open-label, randomized and controlled non-inferiority operative trial. The main goal of this clinical trial is to evaluate the non-inferiority of minimally invasive radical hysterectomy in contrast to abdominal radical hysterectomy in patients with early-stage cervical cancer. In the case of SHAPE criteria, surgery may also be performed as minimally invasive or abdominal simple hysterectomy. The primary criterion for assessment is disease-free survival (DFS). As secondary outcomes, overall survival (OS), disease recurrence, quali

Trial Details

NCT ID
NCT06489795
Phase
NA
Sponsor
Hannover Medical School
Status
RECRUITING
Cancer Type
Cervical Cancer
Interventions
  • Laparoscopic or robot-assisted radical/simple hysterectomy
  • Abdominal radical/simple hysterectomy
Locations (sample)
  • Ludwigsburg, Baden-Wurttemberg, Germany|48.89731,9.19161
  • Tübingen, Baden-Wurttemberg, Germany|48.52266,9.05222
  • Bad Homburg, Hesse, Germany|50.22683,8.61816
  • Göttingen, Lower Saxony, Germany|51.53443,9.93228
  • Hanover, Lower Saxony, Germany|52.37052,9.73322

Key Eligibility Criteria

  • Histologically confirmed primary adenocarcinoma, squamous cell carcinoma or adenosquamous carcinoma of the uterine cervix
  • Patients with FIGO stage IA2, IB1, or IB2 disease (\<4 cm)
  • Patients undergoing radical hysterectomy according either to Type II or III (Piver Classification) or to Type B or C (Querleu and Morrow classifica…
  • Simple hysterectomy can be considered for patients with low-risk early-stage cervical cancer (SHAPE criteria: tumor \< 2cm, \< 10 mm depth of strom…

For full eligibility, visit ClinicalTrials.gov.

Check If You May Be Eligible

Trialify translates complex eligibility criteria into plain yes-or-no questions to help you understand if this trial might be right for you.

Find Cervical Cancer Trials on Trialify →