Nordic ORgan Preservation Pilot Approach Nonrandomised Single-Arm Trial for Non-Operative Management of Rectal Cancer

The goal of this one-arm clinical trial is to implement and study the oncological outcomes of nonoperative management of rectal cancer having complete clinical response to neoadjuvant therapy. The main questions to answer are * if the oncological results of nonoperative management after Nordic practice in chemoradiotherapy indications differ from experiences elsewhere * what is the organ preservation rate * what is the local regrowth rate

Trial Details

NCT ID
NCT06328361
Phase
NA
Sponsor
Tampere University Hospital
Status
RECRUITING
Cancer Type
Colorectal Cancer
Interventions
  • Nonoperative surveillance
Locations (sample)
  • Tallinn, Estonia|59.43696,24.75353
  • Tallinn, Estonia|59.43696,24.75353
  • Tallinn, Estonia|59.43696,24.75353
  • Tartu, Estonia|58.38062,26.72509
  • Helsinki, Finland|60.16952,24.93545

Key Eligibility Criteria

  • Histopathological verification of primary rectal adenocarcinoma
  • Complete clinical response at response assessment after neoadjuvant therapy
  • Informed consent to organ preservation study

For full eligibility, visit ClinicalTrials.gov.

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