Thoracic Radiotherapy for Patients With Metastatic (Stage IV) Non-Small Cell Lung Cancer at High Risk of Symptomatic Progression Within the Thorax

Patients with metastatic non small cell lung cancer with high risk location or size are treated with prophylactic radiation therapy in conjunction with standard of care systemic therapy.

Trial Details

NCT ID

NCT06262321

Phase

PHASE2

Sponsor

University of Rochester

Status

RECRUITING

Cancer Type

Lung Cancer

Interventions

Prophylactic Palliative Radiotherapy

Locations (sample)

Rochester, New York, United States|43.15478,-77.61556

Key Eligibility Criteria

Pathologic diagnosis of Non-Small Cell Lung Cancer (NSCLC) without targetable/oncogene driven mutations (i.e., EGFR mutations, ALK-rearrangement, R…
T1-4(or Tx)N0-3M1a-c, Stage IV disease (using the 8th edition of the AJCC staging manual) or metastatic recurrence of primary Stage I-III NSCLC tha…
Thoracic lung and/or nodal lesion(s) amenable to palliative chest radiotherapy.
All subjects are required to have one or more of the following high-risk features: a) a non-central primary lung lesion ≥5 cm in size (at least T3 …

For full eligibility, visit ClinicalTrials.gov.

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