Safety & Efficacy of Ischemic Preconditioning by Embolization of the Inferior Mesenteric Artery in Surgery for Tumors of Lower and Middle Rectum

The present study will investigate the safety of inferior mesenteric artery embolization prior to rectal surgery, according to IDEAL recommendations (Lancet 2009). It aims to assess the safety of endovascular embolization of the inferior mesenteric artery prior to surgery in patients with rectal tumors, and estimate the potential benefits in terms of time to surgery and the occurrence of post-operative fistulas.The study will also assess the impact of subacute ischemia induced by IMA embolization on colonic vasculature remodeling, colonic ischemic suffering, altered hemostasis and initiation o

Trial Details

NCT ID
NCT06236633
Phase
NA
Sponsor
Centre Hospitalier Universitaire de Nīmes
Status
RECRUITING
Cancer Type
Colon Cancer Colorectal Cancer
Interventions
  • Ischemic preconditioning
  • Arteriogram
Locations (sample)
  • Montpellier, France|43.61093,3.87635
  • Montpellier, France|43.61093,3.87635
  • Nîmes, France|43.83665,4.35788

Key Eligibility Criteria

  • Patients with rectal cancer eligible for surgery with ligation at the origin of the inferior mesenteric artery.
  • Patients with free, informed consent.
  • Patients affiliated to or benefiting from a health insurance plan.

For full eligibility, visit ClinicalTrials.gov.

Check If You May Be Eligible

Trialify translates complex eligibility criteria into plain yes-or-no questions to help you understand if this trial might be right for you.

Find Colon Cancer Colorectal Cancer Trials on Trialify →