Androgen Suppression Combined With Nodal Irradiation and Dose Escalated Prostate Treatment

This study is being done to answer the following question: Is the strategy to give higher doses of radiotherapy treatment over a shorter period of time using special equipment and fewer treatments (also known as Stereotactic Body Radiation Therapy or SBRT) as effective as usual external radiation therapy given with a brachytherapy boost (which involves radiation sources inserted directly into the prostate)?

Trial Details

NCT ID
NCT06235697
Phase
PHASE3
Sponsor
Canadian Cancer Trials Group
Status
RECRUITING
Cancer Type
Prostate Cancer
Interventions
  • Radiation
  • Radiation SBRT only
  • ADT
Locations (sample)
  • Antioch, California, United States|38.00492,-121.80579
  • Dublin, California, United States|37.70215,-121.93579
  • Fremont, California, United States|37.54827,-121.98857
  • Fresno, California, United States|36.74773,-119.77237
  • Fresno, California, United States|36.74773,-119.77237

Key Eligibility Criteria

  • Histologically confirmed adenocarcinoma of the prostate diagnosed within the last 9 months
  • Participants with unfavourable risk prostate cancer are eligible according to the following NCCN classification guidelines (Version 4.2022 - May 10…
  • Unfavourable-intermediate risk - has one or more of the following:
  • 2 or 3 Intermediate Risk Factors (IRFs): cT2b-cT2c, Gleason 7 (grade group 2 or 3), and/or PSA 10-20 ng/ml;

For full eligibility, visit ClinicalTrials.gov.

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