Effectiveness of Focal Therapy in Men With Prostate Cancer

In the Netherlands, most men with prostate cancer (PCa) are treated with radical whole-gland treatment, i.e. prostatectomy or radiotherapy. The burden of complications such as incontinence and erectile dysfunction associated with radical treatment is considerable. A recent systematic review by our group has shown that focal therapy of PCa seems to reduce the burden of treatment side-effects in men with intermediate-risk disease, maintaining their quality of life without compromising oncological effectiveness. The costs of side effects that can be prevented are estimated at €5456 per patient, r

Trial Details

NCT ID
NCT06223295
Phase
NA
Sponsor
Radboud University Medical Center
Status
RECRUITING
Cancer Type
Prostate Cancer
Interventions
  • Focal therapy
  • Usual care
Locations (sample)
  • Nijmegen, Gelderland, Netherlands|51.8425,5.85278
  • Etten-Leur, North Brabant, Netherlands|51.57056,4.63726
  • Amsterdam, North Holland, Netherlands|52.37403,4.88969
  • Zwolle, Overijssel, Netherlands|52.5125,6.09444
  • Nieuwegein, Utrecht, Netherlands|52.02917,5.08056

Key Eligibility Criteria

  • Gleason score of 7 (3 + 4 or 4 + 3; ISUP grade 2/3)
  • PSA level of ≤ 20 ng/ml
  • Clinical stage ≤ T2b disease
  • Life expectancy of ≥ 10 years

For full eligibility, visit ClinicalTrials.gov.

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