Simultaneous vs. Staged Resection of Colorectal Cancer With Synchronous Liver Metastases

The SYLMET Trial is a randomized trial to compare simultaneous and two-staged resection of primary colorectal and synchronous liver metastases. This is an investigator-initiated, multicentre, randomized controlled trial to assess complications (primary endpoint), survival, cost-effectiveness, and quality of life (secondary endpoints).This trial will include patients with resectable primary tumour in the colon or upper rectum with less than five liver metastases that is possible to treat with surgical resection and/or ablation (RFA/MWA) at time of evaluation.

Trial Details

NCT ID
NCT06200831
Phase
NA
Sponsor
Oslo University Hospital
Status
RECRUITING
Cancer Type
Liver Cancer
Interventions
  • Staged resection
  • Simultaneous resection
Locations (sample)
  • Oslo, Norway|59.91273,10.74609

Key Eligibility Criteria

  • Age 18-80 years old.
  • Both CRC and liver metastases in situ at time of evaluation.
  • Resectable primary tumor in the colon or upper rectum.
  • Less than 5 liver metastases, evaluated by the multidisciplinary tumor board meeting as possible to treat with surgical resection and/or ablation (…

For full eligibility, visit ClinicalTrials.gov.

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