Safety, Pharmacokinetics, and Clinical Activity of LP-284 in Adult Patients With Relapsed or Refractory Lymphomas and Solid Tumors

The goal of this clinical trial is to evaluate the safety and tolerability of escalating doses of LP-284 and to determine the maximum tolerated dose (MTD) and the recommended Phase 2 dose (RP2D) in patients with relapsed or refractory (R/R) lymphomas and solid tumors. The secondary objectives are to characterize the pharmacokinetics (PK) of LP-284 and to assess clinical activity of LP-284.

Trial Details

NCT ID
NCT06132503
Phase
PHASE1
Sponsor
Lantern Pharma Inc.
Status
RECRUITING
Cancer Type
Lymphoma
Interventions
  • LP-284
Locations (sample)
  • West Valley City, Utah, United States|40.69161,-112.00105

Key Eligibility Criteria

  • Male or female aged ≥ 18 years on the day of signing informed consent.
  • Patient is capable of giving signed informed consent as described in Section 11.3 which includes compliance with the requirements and restrictions …
  • Eastern Cooperative Oncology Group (ECOG) performance status: 0-2 at screening.
  • For Lymphoma patients. At least one bi-dimensionally measurable disease site. The lesion must have a greatest transverse diameter of at least 1.5 c…

For full eligibility, visit ClinicalTrials.gov.

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