Application of High-dose Insulin Therapy to Improve Liver Function and Regeneration

The primary objective of this interventional study is determine if the future liver remnant can be optimized by improving liver function pre-operatively in patients who are scheduled for major hepatectomy. The main questions it aims to answer are: 1. Does high-dose insulin therapy improve liver function in the pre-operative setting? 2. What is the effect of high-dose insulin therapy on liver function and liver regeneration after a liver venous deprivation (LVD) procedure? 3. What is the relationship between volume hypertrophy and function in the regenerating liver? Participants will receive a

Trial Details

NCT ID
NCT06126419
Phase
NA
Sponsor
McGill University Health Centre/Research Institute of the McGill University Health Centre
Status
RECRUITING
Cancer Type
Colon Cancer Colorectal Cancer
Interventions
  • High-Dose Insulin Therapy
Locations (sample)
  • Montreal, Quebec, Canada|45.50884,-73.58781

Key Eligibility Criteria

  • Age \> 18 years old
  • Candidate for major liver resection
  • Resectable colorectal liver metastasis

For full eligibility, visit ClinicalTrials.gov.

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