Single-drug Chemotherapy Plus Immunotherapy in Metastatic Non-small Cell Lung Cancer Elderly Patients

Lung cancer is the cancer with the highest morbidity and mortality among men in the world. The proportion of elderly lung cancer patients in the global lung cancer population is steadily increasing, at the same time, it is also the age group with the highest lung cancer mortality, but there is little evidence for treatment of elderly lung cancer patients. In this study, the investigators set the definition of the elderly to 65 years and older. The progression-free survival (PFS) and overall survival (OS) of immunotherapy plus chemotherapy were higher than those of chemotherapy alone, which es

Trial Details

NCT ID
NCT06032052
Phase
PHASE2
Sponsor
Hubei Cancer Hospital
Status
RECRUITING
Cancer Type
Lung Cancer
Interventions
  • Single drug chemotherapy plus immunotherapy
Locations (sample)
  • Wuhan, Hubei, China|30.58333,114.26667

Key Eligibility Criteria

  • Regardless of sex, age ≥ 65, PS 0-2.
  • metastatic NSCLC of American Joint Committee on Cancer (AJCC) 8th edition confirmed by histology or cytology.
  • No mutation or fusion of common driving genes, such as epidermal growth factor receptor (EGFR), anaplastic lymphoma kinase (ALK), ROS proto-oncogen…
  • (adenocarcinoma requires genetic testing).

For full eligibility, visit ClinicalTrials.gov.

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