Trial of Nab-sirolimus in Patients With Well-differentiated Neuroendocrine Tumors (NETs) of the Gastrointestinal Tract, Lung, or Pancreas Who Have Not Received Prior Treatment With mTOR Inhibitors

A Phase 2 multi-center, open-label, single arm study of nab-sirolimus in patients with well-differentiated neuroendocrine tumors (NETs) of the gastrointestinal tract, lung, or pancreas who have not received prior treatment with mTOR inhibitors

Trial Details

NCT ID
NCT05997056
Phase
PHASE2
Sponsor
Aadi Bioscience, Inc.
Status
RECRUITING
Cancer Type
Pancreatic Neuroendocrine Pancreatic Cancer
Interventions
  • nab-sirolimus
Locations (sample)
  • Newport Beach, California, United States|33.61891,-117.92895
  • Denver, Colorado, United States|39.73915,-104.9847
  • Dallas, Texas, United States|32.78306,-96.80667
  • Milwaukee, Wisconsin, United States|43.0389,-87.90647

Key Eligibility Criteria

  • Patients with functional or non-functional, well-differentiated, locally advanced unresectable or metastatic NETs of the GI tract, lung, or pancrea…
  • Patients with functional NETs may enroll if:
  • the patient has been on a stable dose of an somatostatin analogs for ≥12 weeks and
  • the patient has experienced disease progression while on stable somatostatin analogs dose

For full eligibility, visit ClinicalTrials.gov.

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