Intermittent Androgen Deprivation Therapy in the Era of AR Pathway Inhibitors

This study addresses the global topic of treatment optimization, i.e. achieving similar benefit while reducing the duration of treatment, hence hoping to decrease the burden of side-effects, improve quality-of life and reduce resource utilization. The primary goal of de-escalation is to investigate whether using an intermittent regime results in a similar OS to continuous treatment.

Trial Details

NCT ID
NCT05974774
Phase
PHASE3
Sponsor
European Organisation for Research and Treatment of Cancer - EORTC
Status
RECRUITING
Cancer Type
Prostate Cancer
Interventions
  • iMAB
  • cMAB
Locations (sample)
  • Copenhagen, Denmark|55.67594,12.56553
  • Caen, France|49.18585,-0.35912
  • Grenoble, France|45.17869,5.71479
  • Quint-Fonsegrives, France|43.5852,1.5272
  • Toulouse, France|43.60426,1.44367

Key Eligibility Criteria

  • Patient treated with ADT and an ARPI for mHNPC for 6-12 months and presenting with a PSA ≤ 0.2 ng/mL Note: Patient may have received docetaxel and …
  • Before patient 's enrolment, written informed consent must be given according to ICH/GCP, and national/local regulations

For full eligibility, visit ClinicalTrials.gov.

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