Induction Chemotherapy Combined With Neoadjuvant Immunotherapy for MSS Colon Cancer

This study aims to elucidate the regression effects of neoadjuvant chemotherapy combined with immunotherapy and adjuvant therapy in locally advanced MSS colon cancer.

Trial Details

NCT ID
NCT05914389
Phase
PHASE2
Sponsor
Second Affiliated Hospital, School of Medicine, Zhejiang University
Status
RECRUITING
Cancer Type
Colon Cancer Colorectal Cancer
Interventions
  • Oxaliplatin
  • Capecitabine
  • Anti-PD-L1 Monoclonal Antibody
  • Clostridium butyricum
  • Colectomy
Locations (sample)
  • Hangzhou, Zhejiang, China|30.29365,120.16142

Key Eligibility Criteria

  • Age ≥18 years old and ≤75 years old.
  • Pathologically diagnosed MSS or pMMR-type colon adenocarcinoma.
  • The lower edge of the tumor is more than 12cm from the anus as measured by colonoscopy and the lower edge of the tumor cannot be directly palpated …
  • Enhanced CT stage T3/4 or T1-4N+ without multiple primary tumors or distant metastasis.

For full eligibility, visit ClinicalTrials.gov.

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