Technical Feasibility of Modified Early Post-Operative Intraperitoneal Chemotherapy (mEPIC)

The goal of this prospective phase II unicentric Canadian clinical trial is to clarify the feasibility of modified early post-operative intraperitoneal chemotherapy (mEPIC) following cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) in the clinical context of peritoneal carcinomatosis from colorectal and appendicular neoplasms. The primary objective of this study is to confirm the feasibility of mEPIC by evaluating its completion rate compared to the one of historical standard early post-operative intraperitoneal chemotherapy (EPIC) cohorts. The secondary objec

Trial Details

NCT ID
NCT05913674
Phase
PHASE2
Sponsor
Ciusss de L'Est de l'Île de Montréal
Status
RECRUITING
Cancer Type
Colorectal Cancer
Interventions
  • Modified early post-operative intraperitoneal chemotherapy (mEPIC)
Locations (sample)
  • Montreal, Quebec, Canada|45.50884,-73.58781

Key Eligibility Criteria

  • Patient's age 18 years or older, both genders.
  • In good general health as evidenced by an ECOG score of 0 or 1.
  • Histological diagnosis of appendicular or colorectal tumors with peritoneal carcinomatosis, either synchronous (\< 12 months after primary diagnosi…
  • Complete staging defined as: (1)Computed tomography (CT) scan of the chest, abdomen and pelvis. (2) Positron emission tomography (PET) scan when cl…

For full eligibility, visit ClinicalTrials.gov.

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