Abemaciclib and Letrozole in Patients With Estrogen Receptor-positive Rare Ovarian Cancer

Trial Details

NCT ID

NCT05872204

Phase

PHASE2

Sponsor

Universitaire Ziekenhuizen KU Leuven

Status

RECRUITING

Cancer Type

High-Grade Serous Ovarian Cancer

Interventions

• Abemaciclib
• Letrozole

Locations (sample)

• Liège, Liège, Belgium|50.63373,5.56749
• Ghent, Oost-Vlaanderen, Belgium|51.05,3.71667
• Leuven, Vlaams-Brabant, Belgium|50.87959,4.70093
• Strasbourg, Bas-Rhin, France|48.58392,7.74553
• Bordeaux, Gironde, France|44.84124,-0.58046

Key Eligibility Criteria

• Voluntary written informed consent of the participant or their legally authorized representative has been obtained prior to any screening procedures.
• Use of highly effective methods of birth control; defined as those that, alone or in combination, result in low failure rate (i.e., less than 1% pe…
• Histological confirmation of diagnosis of low-grade serous (original diagnosis of low-grade serous carcinoma or original diagnosis of serous border…
• For Stage 1: only patients where platinum is still an option are eligible with no limitations in prior chemotherapy regimens and a maximum of 2 pri…

For full eligibility, visit ClinicalTrials.gov.

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