COLLISION RELAPSE Trial

The primary objective is to demonstrate superiority of neoadjuvant systemic therapy followed by repeat local treatment as compared to upfront repeat local treatment in patients with at least one locally treatable recurrent CRLM in the absence of extrahepatic disease.

Trial Details

NCT ID
NCT05861505
Phase
PHASE3
Sponsor
Amsterdam UMC, location VUmc
Status
RECRUITING
Cancer Type
Colon Cancer Colorectal Cancer
Interventions
  • Neoadjuvant systemic therapy (CAPOX+/-B FOLFOX+/-B FOLFIRI+/-B)
  • Repeat local treatment
Locations (sample)
  • Amsterdam, Netherlands|52.37403,4.88969

Key Eligibility Criteria

  • Age \>18 years
  • Good performance status (ECOG 0-2 // ASA 1-3)
  • Histological documentation of primary colorectal tumor
  • Local treatment performed for initial CRLM

For full eligibility, visit ClinicalTrials.gov.

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