Relapsed Follicular Lymphoma Randomised Trial Against Standard ChemoTherapy

The aim of the REFRACT clinical trial is to find new therapies with improved outcomes compared to the current standard treatment available, in patients with relapsed or refractory follicular lymphoma. This will be done by comparing patients who have received a new treatment against patients who receive standard treatment based on their response to the treatment received.

Trial Details

NCT ID
NCT05848765
Phase
PHASE2
Sponsor
University of Birmingham
Status
RECRUITING
Cancer Type
Lymphoma
Interventions
  • Epcoritamab
  • Lenalidomide
  • Rituximab
  • Obinutuzumab
  • Bendamustine
  • Vincristine
Locations (sample)
  • Aberdeen, United Kingdom|57.14369,-2.09814
  • Belfast, United Kingdom|54.59682,-5.92541
  • Birmingham, United Kingdom|52.48142,-1.89983
  • Blackpool, United Kingdom|53.81667,-3.05
  • Cambridge, United Kingdom|52.2,0.11667

Key Eligibility Criteria

  • Biopsy proven relapsed or refractory CD20 positive, grade 1-3a follicular lymphoma (biopsy within 3 months of trial entry)
  • Aged 18 years or over
  • Advanced disease that in the opinion of the treating physician requires treatment
  • Patient suitable for standard available therapy at the Investigator's discretion

For full eligibility, visit ClinicalTrials.gov.

Check If You May Be Eligible

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