The Effect of Toripalimab Plus Radiotherapy in Patients With Operable Stage II-IIIA (N+) Non Small Cell Lung Cancer

This randomized phase II trial is to explore the clinical efficacy, safety and feasibility of neoadjuvant immunotherapy plus radiotherapy compared with neoadjuvant immunotherapy plus chemotherapy in operable stage II-IIIA (N+) non small cell lung cancer (NSCLC) and the optimal radiotherapy pattern.

Trial Details

NCT ID
NCT05798845
Phase
PHASE2
Sponsor
Shanghai Chest Hospital
Status
RECRUITING
Cancer Type
Lung Cancer
Interventions
  • SBRT+LDRT
  • Toripalimab
  • Chemotherapy drug
Locations (sample)
  • Shanghai, Shanghai Municipality, China|31.22222,121.45806

Key Eligibility Criteria

  • Age 18 to 75 years old, gender is not limited.
  • ECOG performance status 0-1.
  • non-small cell lung cancer diagnosed by pathology.
  • sufficient tumor tissue available for biomarker analysis.

For full eligibility, visit ClinicalTrials.gov.

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