Evaluating Safety and Efficacy of Prostate-sparing Radical Cystectomy

The purpose of this clinical trial is to determine if prostate-capsule-sparing cystectomy improves functional outcomes without comprising oncologic outcomes in male patients receiving a radical cystectomy. Patients will be randomized to one of two groups: prostate capsule-sparing radical cystectomy or nerve-sparing radical cystectomy. Patients will be monitored following standard of care guidelines and clinical data will be collected. Patients in both groups will be asked to complete an erectile function questionnaire at multiple timepoints. Patients who receive an orthotopic neobladder will b

Trial Details

NCT ID
NCT05792722
Phase
NA
Sponsor
Johns Hopkins University
Status
RECRUITING
Cancer Type
Prostate Cancer
Interventions
  • Prostate capsule-sparing radical cystectomy
  • Nerve sparing radical cystectomy
Locations (sample)
  • Washington D.C., District of Columbia, United States|38.89511,-77.03637
  • Baltimore, Maryland, United States|39.29038,-76.61219

Key Eligibility Criteria

  • Subjects with pathologically confirmed bladder cancer scheduled for radical cystectomy
  • Variant histologies of bladder cancer permitted
  • Neoadjuvant therapy permitted
  • Age \> 18 years old

For full eligibility, visit ClinicalTrials.gov.

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