Study of Effect of Azeliragon in Patients Refractory to Prior Treatment of Metastatic Pancreatic Cancer

This is an open label study to determine the safety and preliminary evidence of a therapeutic effect of azeliragon in patients refractory to prior treatment of metastatic pancreatic cancer.

Trial Details

NCT ID
NCT05766748
Phase
PHASE1 / PHASE2
Sponsor
Cantex Pharmaceuticals
Status
RECRUITING
Cancer Type
Pancreatic Cancer
Interventions
  • Azeliragon
Locations (sample)
  • Los Angeles, California, United States|34.05223,-118.24368
  • Boca Raton, Florida, United States|26.35869,-80.0831
  • Eugene, Oregon, United States|44.05207,-123.08675
  • Pittsburgh, Pennsylvania, United States|40.44062,-79.99589
  • Greenville, South Carolina, United States|34.85262,-82.39401

Key Eligibility Criteria

  • Patient must have histologically confirmed locally advanced or metastatic adenocarcinoma of the pancreas for which potential curative measures, suc…
  • Patient should have previously been treated with a Gemcitabine/Abraxane or FOLFIRINOX- based regimen.
  • Toxicity from prior chemotherapy other than alopecia has recovered to Grade ≤ 1 (CTCAE 1.0) or are at baseline (such as stable G2 neuropathy).
  • Male or non-pregnant and non-lactating female and ≥ 18 to ≤ 80 years of age.

For full eligibility, visit ClinicalTrials.gov.

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