Evaluate REC-4881 in Participants With Familial Adenomatous Polyposis (FAP)

This is a multicenter, two-part trial in participants with FAP.

Trial Details

NCT ID
NCT05552755
Phase
PHASE1 / PHASE2
Sponsor
Recursion Pharmaceuticals Inc.
Status
RECRUITING
Cancer Type
Colorectal Cancer
Interventions
  • REC-4881
  • Placebo
Locations (sample)
  • Scottsdale, Arizona, United States|33.50921,-111.89903
  • Tucson, Arizona, United States|32.22174,-110.92648
  • San Diego, California, United States|32.71571,-117.16472
  • Naples, Florida, United States|26.14234,-81.79596
  • Orlando, Florida, United States|28.53834,-81.37924

Key Eligibility Criteria

  • Male or female and ≥ 18 years of age
  • Have provided written informed consent to participate in the study
  • Diagnosis of phenotypic classical FAP with disease involvement of the duodenum or the residual colon/rectum/pouch as the primary disease site.
  • Genetic diagnosis of FAP with APC gene mutation (Part 2 only).

For full eligibility, visit ClinicalTrials.gov.

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