Olaparib in Combination With Pembrolizumab for Advanced Uveal Melanoma

This is a prospective phase II multi-center trial of the combination of the PARP inhibitor olaparib with the immune checkpoint inhibitor pembrolizumab in advanced uveal melanoma.

Trial Details

NCT ID
NCT05524935
Phase
PHASE2
Sponsor
H. Lee Moffitt Cancer Center and Research Institute
Status
RECRUITING
Cancer Type
Melanoma
Locations (sample)
  • Tampa, Florida, United States|27.94752,-82.45843

Key Eligibility Criteria

  • Male or female participants who are at least 18 years of age on the day of signing informed consent with histologically confirmed diagnosis of meta…
  • Male participants: A male participant must agree to use a contraception as detailed in Appendix 3 of this protocol during the treatment period and …
  • Female participants: A female participant is eligible to participate if she is not pregnant (see Appendix 3), not breastfeeding, and at least one o…
  • The participant (or legally acceptable representative if applicable) provides written informed consent for the trial.

For full eligibility, visit ClinicalTrials.gov.

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