Carbon Ion Radiation Therapy in the Treatment of Mucous Melanomas of the Female Lower Genital Tract

The present monocentric prospective phase 2 study aims to reproduce the results obtained at NIRS thus offering the possibility of obtaining a promising rate of progression-free survival (PFS) and local control (LC) in patients diagnosed with mucosal melanoma of lower genital tract. Systemic treatment with immunotherapy is not the subject of this study but is allowed both in the neoadjuvant and sequential regimens. Melanomas have always been considered poorly radiosensitive. It is now accepted that high LET (Linear Energy Transfer) particle beams, such as carbon ions, can offer a biological ad

Trial Details

NCT ID

NCT05478876

Phase

NA

Sponsor

CNAO National Center of Oncological Hadrontherapy

Status

RECRUITING

Cancer Type

Mucosal Melanoma Melanoma

Interventions

• carbon ion radiation therapy CIRT

Locations (sample)

• Pavia, Italy|45.19205,9.15917

Key Eligibility Criteria

• Histological diagnosis
• Absence of skin extension
• N + (only if confined to the groin and pelvis)
• Age between 20-80 years

For full eligibility, visit ClinicalTrials.gov.

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