Concurrent Fluorescence and Sonographically Guided Eradication of High-grade Gliomas and Metastases

The objective of the study is to determine whether the combined use of intraoperative fluorescence with 5-aminolevulinic acid (5-ALA) and sonography can achieve a higher rate of gross total resection in hemispheric high-grade gliomas and brain metastases compared to intraoperative fluorescence with 5-ALA alone.

Trial Details

NCT ID
NCT05474573
Phase
NA
Sponsor
Sklifosovsky Institute of Emergency Care
Status
RECRUITING
Cancer Type
Brain Cancer
Interventions
  • Combined ultrasound and fluorescence-guided brain tumor resection
  • Fluorescence-guided brain tumor resection
Locations (sample)
  • Moscow, Russia|55.75204,37.61781

Key Eligibility Criteria

  • single high-grade glioma
  • solitary, single or multiple brain metastases of solid tumors of any primary origin
  • newly diagnosed
  • Karnofsky Performance Status 60-100%

For full eligibility, visit ClinicalTrials.gov.

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