A Study to Evaluate Safety, Drug Levels and Effectiveness of CC-92480 (BMS-986348) in Combination With Other Treatments in Participants With Relapsed or Refractory Multiple Myeloma

The purpose of this study is to assess the safety, tolerability and preliminary effectiveness of CC-92480 (BMS-986348) in novel therapeutic combinations for the treatment of Relapsed or Refractory Multiple Myeloma (RRMM).

Trial Details

NCT ID
NCT05372354
Phase
PHASE1 / PHASE2
Sponsor
Bristol-Myers Squibb
Status
RECRUITING
Cancer Type
Relapsed/Refractory Multiple Myeloma
Interventions
  • CC-92480
  • Tazemetostat
  • BMS-986158
  • Trametinib
  • Dexamethasone
Locations (sample)
  • Birmingham, Alabama, United States|33.52066,-86.80249
  • Baltimore, Maryland, United States|39.29038,-76.61219
  • Boston, Massachusetts, United States|42.35843,-71.05977
  • Hackensack, New Jersey, United States|40.88593,-74.04347
  • New York, New York, United States|40.71427,-74.00597

Key Eligibility Criteria

  • Relapsed or refractory multiple myeloma (MM) and must:
  • Have documented disease progression during or after their last myeloma therapy.
  • For Part 1 Dose Finding: Be refractory to, intolerant to, or not a candidate for available, established therapies known to provide clinical benefit…
  • Must have measurable disease.

For full eligibility, visit ClinicalTrials.gov.

Check If You May Be Eligible

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