Novel Targeted Drugs Combined With R-ICE Regimen in Relapsed and Refractory Diffuse Large B-cell Lymphoma

A single-center, open, single-arm clinical study of the efficacy and safety of a novel targeted agent in combination with R-ICE in the treatment of relapsed and refractory diffuse Large B-cell lymphoma.

Trial Details

NCT ID
NCT05348213
Phase
PHASE2
Sponsor
Ruijin Hospital
Status
RECRUITING
Cancer Type
Lymphoma
Interventions
  • Zanubrutinib plus R-ICE
  • Decitabine plus R-ICE
  • Chidamide plus R-ICE
  • Tofacitinib plus R-ICE
  • Pomalidomide plus R-ICE
Locations (sample)
  • Shanghai, Shanghai Municipality, China|31.22222,121.45806

Key Eligibility Criteria

  • DLBCL was confirmed by histology according to world Health Organization (WHO) disease classification (excluding primary central lymphoma and HIV-as…
  • There are evaluable lesions detected by PET/CT;
  • Life expectancy of more than 3 months;
  • Prior treatment with sufficient first-line anti-lymphoma therapy, no remission within 90 days of the last administration, or disease progression af…

For full eligibility, visit ClinicalTrials.gov.

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