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NCT05348213
Novel Targeted Drugs Combined With R-ICE Regimen in Relapsed and Refractory Diffuse Large B-cell Lymphoma
A single-center, open, single-arm clinical study of the efficacy and safety of a novel targeted agent in combination with R-ICE in the treatment of relapsed and refractory diffuse Large B-cell lymphoma.
Trial Details
NCT ID NCT05348213
Phase PHASE2
Sponsor Ruijin Hospital
Status RECRUITING
Cancer Type Lymphoma
Interventions Zanubrutinib plus R-ICE Decitabine plus R-ICE Chidamide plus R-ICE Tofacitinib plus R-ICE Pomalidomide plus R-ICE
Locations (sample) Shanghai, Shanghai Municipality, China|31.22222,121.45806
Key Eligibility Criteria
DLBCL was confirmed by histology according to world Health Organization (WHO) disease classification (excluding primary central lymphoma and HIV-as… There are evaluable lesions detected by PET/CT; Life expectancy of more than 3 months; Prior treatment with sufficient first-line anti-lymphoma therapy, no remission within 90 days of the last administration, or disease progression af…
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