Post-Autologous Transplant Maintenance With Isatuximab and Lenalidomide in Minimal Residual Disease Positive Multiple Myeloma

This is a phase II study where patients will undergo isatuximab and lenalidomide maintenance if they are MRD-positive after Autologous Stem Cell Transplant (ASCT)

Trial Details

NCT ID
NCT05344833
Phase
PHASE2
Sponsor
University of Illinois Chicago
Status
RECRUITING
Cancer Type
Multiple Myeloma
Interventions
  • Isatuximab
  • Lenalidomide
Locations (sample)
  • Chicago, Illinois, United States|41.85003,-87.65005
  • Salt Lake City, Utah, United States|40.76078,-111.89105

Key Eligibility Criteria

  • Age \> 18 years
  • Patients must have a confirmed diagnosis of multiple myeloma according to IMWG criteria. Patients with smoldering multiple myeloma, or plasma cell …
  • R-ISS stage 1, 2 or 3 at diagnosis. If stage at diagnosis is not known, patient may be enrolled if the intent is to treat with post -ASCT maintenan…
  • Received up to or less than 2 lines of therapy prior to ASCT (as long as they did not meet IMWG refractory disease for CD38 monoclonal antibody or …

For full eligibility, visit ClinicalTrials.gov.

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