Study to Assess the Safety, Tolerability of JPI-547 in Combination With Modified FOLFIRINOX or Gemcitabine-nab-paclitaxel in Patients With Locally Advanced and Metastatic Pancreatic Cancer

The purpose of this study is to assess the safety, tolerability and efficacy of JPI-547 in combination with modified FOLFIRINOX (mFOLFIRINOX) or Gemcitabine-nab-paclitaxel (GemAbraxne) in patients with locally advanced and metastatic pancreatic cancer

Trial Details

NCT ID
NCT05257993
Phase
PHASE1 / PHASE2
Sponsor
Onconic Therapeutics Inc.
Status
RECRUITING
Cancer Type
Pancreatic Cancer
Interventions
  • JPI-547
  • modified FOLFIRINOX
  • Gemcitabine-nab-paclitaxel
Locations (sample)
  • Gyeonggi-do, South Korea|37.58944,126.76917
  • Seoul, South Korea|37.566,126.9784
  • Seoul, South Korea|37.566,126.9784
  • Seoul, South Korea|37.566,126.9784

Key Eligibility Criteria

  • \[Phase 1b/2\]
  • Histologically or cytologically confirmed inoperable locally advanced or metastatic pancreatic ductal adenocarcinoma (PDAC)
  • Those with at least one measurable lesion in accordance with RECIST 1.1
  • Those with Eastern Cooperative Oncology Group (ECOG) performance status 0 or 1

For full eligibility, visit ClinicalTrials.gov.

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