Axillary Lymph Node Treatment Guided by Naocarbon Tracing After Neoadjuvant Chemotherapy

For patients with early breast cancer with negative axillary lymph nodes, sentinel lymph node biopsy (SLNB) can largely avoid complications such as upper limb lymphoedema caused by axillary lymph node dissection (ALND). Locally advanced breast cancer requires neoadjuvant chemotherapy (NAC), based on the breast cancer treatment guidelines. In addition to shrinking the primary breast lesion, NAC can reduce the stage for axillary positive lymph nodes. Therefore, in recent years clinicians have been considering SLNB for patients whose axillary lymph nodes have turned negative after NAC. After veri

Trial Details

NCT ID
NCT05241119
Phase
NA
Sponsor
Shengjing Hospital
Status
RECRUITING
Cancer Type
Breast Cancer
Interventions
  • SLNB
  • pALND
  • ALND
Locations (sample)
  • Shenyang, Liaoning, China|41.79222,123.43278
  • Shenyang, Liaoning, China|41.79222,123.43278

Key Eligibility Criteria

  • invasive breast cancer confirmed by biopsy and histology;
  • based on prone CT scan and Doppler ultrasound, axillary stage cN2-3;
  • agree and meet the requirements for NAC;
  • meet surgical requirements and agree to undergo surgery after NAC;

For full eligibility, visit ClinicalTrials.gov.

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