Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

This phase III trial compares the effect of open thoracic surgery (thoracotomy) to thoracoscopic surgery (video-assisted thoracoscopic surgery or VATS) in treating patients with osteosarcoma that has spread to the lung (pulmonary metastases). Open thoracic surgery is a type of surgery done through a single larger incision (like a large cut) that goes between the ribs, opens up the chest, and removes the cancer. Thoracoscopy is a type of chest surgery where the doctor makes several small incisions and uses a small camera to help with removing the cancer. This trial is being done evaluate the tw

Trial Details

NCT ID
NCT05235165
Phase
PHASE3
Sponsor
Children's Oncology Group
Status
RECRUITING
Cancer Type
Osteosarcoma Sarcoma
Interventions
  • Biospecimen Collection
  • Computed Tomography
  • Questionnaire Administration
  • Thoracoscopy
  • Thoracotomy
Locations (sample)
  • Birmingham, Alabama, United States|33.52066,-86.80249
  • Anchorage, Alaska, United States|61.21806,-149.90028
  • Kingman, Arizona, United States|35.18944,-114.05301
  • Phoenix, Arizona, United States|33.44838,-112.07404
  • Little Rock, Arkansas, United States|34.74648,-92.28959

Key Eligibility Criteria

  • Patients must be \< 50 years at the time of enrollment.
  • Patients must have =\< 4 nodules per lung consistent with or suspicious for metastases, with at least one of which being \>= 3 mm and all of which …
  • Note: Patient must have eligibility confirmed by rapid central imaging review.
  • Lung nodules must be considered resectable by either open thoracotomy or thoracoscopic surgery. Determination of resectability is made by the insti…

For full eligibility, visit ClinicalTrials.gov.

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