Pembrolizumab and Brentuximab Vedotin vs GDP and Stem Cell Transplant for Relapsed/Refractory Hodgkin Lymphoma

This study is being done to determine if two new drugs can shrink or eliminate classical Hodgkins lymphoma.

Trial Details

NCT ID
NCT05180097
Phase
PHASE2
Sponsor
Canadian Cancer Trials Group
Status
RECRUITING
Cancer Type
Lymphoma
Interventions
  • Gemcitabine
  • Dexamethasone
  • Cisplatin
  • Brentuximab vedotin
  • Pembrolizumab
Locations (sample)
  • Concord, New South Wales, Australia|-33.84722,151.10381
  • Nowra, New South Wales, Australia|-34.88422,150.60036
  • Wollongong, New South Wales, Australia|-34.424,150.89345
  • Adelaide, South Australia, Australia|-34.92866,138.59863
  • Heidelberg, Victoria, Australia|-37.75,145.06667

Key Eligibility Criteria

  • History of classic Hodgkin lymphoma by histopathology and now have relapsed or refractory disease after anthracycline-containing chemotherapy and e…
  • 18 years of age or greater
  • ECOG performance status 0-1
  • Clinically and/or radiologically measurable disease as per the Lugano 2014 classification

For full eligibility, visit ClinicalTrials.gov.

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