CLN-049 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)

CLN-049-001 is a Phase 1/2, open-label, multicenter, first-in-human trial of CLN-049 in patients with Relapsed/Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)

Trial Details

NCT ID
NCT05143996
Phase
PHASE1 / PHASE2
Sponsor
Cullinan Therapeutics Inc.
Status
RECRUITING
Cancer Type
Leukemia
Interventions
  • CLN-049
Locations (sample)
  • Birmingham, Alabama, United States|33.52066,-86.80249
  • Phoenix, Arizona, United States|33.44838,-112.07404
  • Duarte, California, United States|34.13945,-117.97729
  • Los Angeles, California, United States|34.05223,-118.24368
  • Aurora, Colorado, United States|39.72943,-104.83192

Key Eligibility Criteria

  • Aged ≥ 18 years of age.
  • Patient has a confirmed diagnosis of recurrent or refractory AML or MDS:
  • Parts A, B, C:
  • i. AML either de novo or secondary ii. MDS with at least 5% blasts that is relapsed after or refractory to hypomethylating agent (HMA) therapy iii.…

For full eligibility, visit ClinicalTrials.gov.

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