A Study of GC101 TIL in Advanced Melanoma (10hospital)

This study is to investigate the safety and efficacy of tumor infiltrating lymphocyte (TIL) therapy in patients with advanced melanoma. Autologous TILs are expanded from tumor resections or biopsies and infused i.v. into the patient after NMA lymphodepletion treatment with hydroxychloroquine(600mg,single-dose) and cyclophosphamide.

Trial Details

NCT ID
NCT05098184
Phase
EARLY_PHASE1
Sponsor
Shanghai Juncell Therapeutics
Status
RECRUITING
Cancer Type
Melanoma
Interventions
  • Tumor Infiltrating Lymphocyte
Locations (sample)
  • Shanghai, China|31.22222,121.45806

Key Eligibility Criteria

  • Age: 18 years to 75 years;
  • Histologically diagnosed as primary/relapsed/metastasized melanoma;
  • Expected life-span more than 3 months;
  • Karnofsky≥60% or ECOG score 0-2;

For full eligibility, visit ClinicalTrials.gov.

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