Pre-operative SABR With and Without Caloric Restriction for Early Stage Breast Cancer

This phase II trial studies the effect of calorie reduction while undergoing stereotactic ablative radiation therapy in treating patients with breast cancer. Stereotactic ablative radiation therapy (sABR) is a highly focused radiation treatment that gives an intense dose of radiation concentrated on a tumor, while limiting the dose to the surrounding organ. Giving SABR before surgery may make the tumor smaller. Adding dietary restrictions in combination with radiation therapy may help increase local control and decrease the spread of the cancer to other places in the body. The purpose of this

Trial Details

NCT ID
NCT04959474
Phase
NA
Sponsor
Thomas Jefferson University
Status
RECRUITING
Cancer Type
Triple Negative (TNBC) Breast Cancer
Interventions
  • Best Practice
  • Stereotactic Body Radiation Therapy
  • Resection
  • Sentinel Lymph Node Biopsy
  • Dietary Intervention
  • Questionnaire Administration
Locations (sample)
  • Philadelphia, Pennsylvania, United States|39.95238,-75.16362

Key Eligibility Criteria

  • • Patients with pathologically proven DCIS or invasive breast cancer histologies
  • Willing and able to provide informed consent
  • Willing and able to comply with study treatments including dietary intervention
  • Body mass index (BMI) \>= 21 at time of enrollment

For full eligibility, visit ClinicalTrials.gov.

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