MR-guided Prostate Stereotactic Body Radiotherapy in Seven Days

The Proseven trial is a prospective interventional study that will evaluate the toxicity and efficacy of MR-guided stereotactic body radiotherapy (SBRT) in the profound hypofractionated treatment of prostate cancer. Patients will be treated in 5 daily fractions within a short overall treatment time (OTT) of 7 days. A simultaneous integrated boost (SIB) will be delivered to the intraprostatic dominant lesion (if present) in this study. Besides a potential biological impact of this innovative prostate SBRT treatment, the reduced OTT offers also benefits in terms of patient convenience. The prima

Trial Details

NCT ID
NCT04896801
Phase
NA
Sponsor
Universitair Ziekenhuis Brussel
Status
RECRUITING
Cancer Type
Prostate Cancer
Interventions
  • MR-guided RT
Locations (sample)
  • Brussels, Belgium|50.85045,4.34878

Key Eligibility Criteria

  • Age \> 18 y
  • Histologically confirmed prostate adenocarcinoma
  • Low risk: cT1c-T2a, Gleason score 6, PSA \< 10ng/mL
  • Favorable intermediate risk: 1 intermediate risk factor, Gleason 3+4 or less, \< 50% positive biopsy cores)

For full eligibility, visit ClinicalTrials.gov.

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