Additional Treatment for Isolated Local Pancreatic Cancer Recurrence Using Stereotactic Body Radiation Therapy

A randomized controlled trial, nested within an existing prospective cohort (Dutch Pancreatic Cancer Project; PACAP) according to the 'trials within cohorts' (TwiCs) design in which the effect of additional local ablative therapy compared to current standard of care alone, on survival after recurrence in patients with isolated local pancreatic ductal adenocarcinoma (PDAC) recurrence. The most important secondary endpoint is quality of life. Other secondary endpoints are treatment response, acute and late toxicity, overall survival, progression-free survival, local progression-free survival, di

Trial Details

NCT ID
NCT04881487
Phase
NA
Sponsor
UMC Utrecht
Status
RECRUITING
Cancer Type
Pancreatic Cancer
Interventions
  • Additional stereotactic body radiation therapy
Locations (sample)
  • Amsterdam, North Holland, Netherlands|52.37403,4.88969
  • Rotterdam, South Holland, Netherlands|51.9225,4.47917
  • Utrecht, Utrecht, Netherlands|52.09083,5.12222

Key Eligibility Criteria

  • Participation in the PACAP cohort with written informed consent for being randomized in future studies
  • Isolated local recurrence after primary PDAC resection
  • Minimum age of 18 years

For full eligibility, visit ClinicalTrials.gov.

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