Functional Lung Avoidance SPECT-guided Radiation Therapy of Lung Cancer

Study aims to determine if functional lung avoidance based on perfusion single photon emission (SPECT)/CT scan, improves toxicity outcomes for patients with advanced lung cancer undergoing chemo-radiotherapy. Functional avoidance implies a dose plan that takes functional distribution in the lung into account, and avoids highly functional lung volumes sparing them from radiation.

Trial Details

NCT ID
NCT04676828
Phase
NA
Sponsor
University of Aarhus
Status
RECRUITING
Cancer Type
Lung Cancer
Interventions
  • Single-photon-emission CT scan
Locations (sample)
  • Sydney, New South Wales, Australia|-33.86785,151.20732
  • Aarhus, Denmark|56.15674,10.21076

Key Eligibility Criteria

  • histologically verified lung cancer (small-cell and non-small cell lung cancer)
  • referred for radiotherapy with curative intent
  • radiation dose of 60-66 Gy given in 2-Gy fractions, other dose levels and fractionation schedules accepted, as per site standard
  • concurrent chemotherapy is accepted

For full eligibility, visit ClinicalTrials.gov.

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